@article{Dachlika_Stern_Rotem_Porath_2023, title={Formation of Dimers Composed of a Single Short dsDNA Connecting Two Gold Nanoparticles}, volume={1}, url={https://www.journal.riverpublishers.com/index.php/jsame/article/view/188}, DOI={10.13052/same2245-4551.114}, abstractNote={<p><span dir="ltr" style="left: 21.92%; top: 51.49%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.04162);" role="presentation">We report synthesis of dimers composed of a</span> <span dir="ltr" style="left: 56.95%; top: 51.49%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(0.992079);" role="presentation">single</span> <span dir="ltr" style="left: 62%; top: 51.49%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.00576);" role="presentation">short double-stranded</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 53.03%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.02238);" role="presentation">(ds)DNA molecule connecting two gold nanoparticles (GNPs). Such struc-</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 54.57%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.03632);" role="presentation">tures may be useful for electrical transport measurements through dsDNA</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 56.11%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.04251);" role="presentation">molecules and for other research purposes. When the DNA molecules are</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 57.65%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.03111);" role="presentation">short with respect to the size of the GNP, gel electrophoresis cannot separ-</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 59.19%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.0336);" role="presentation">ate GNPs with different numbers of DNA molecules attached to them. We</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 60.72%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.04065);" role="presentation">present two methods to separate GNPs connected to single short thiolated</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 62.26%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.04618);" role="presentation">single-stranded (ss)DNA. The separation is performed by hybridizing the</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 63.8%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.02806);" role="presentation">DNA/GNP conjugates with long, partially complementary, ssDNA or with</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 65.34%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.03681);" role="presentation">complementary ssDNA connected to GNPs of smaller size. The separated</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 66.88%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(1.05503);" role="presentation">GNPs with a single short ssDNA were used to form dimers consisting of</span><br role="presentation"><span dir="ltr" style="left: 21.92%; top: 68.42%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(0.998843);" role="presentation">GNPs connected by a</span> <span dir="ltr" style="left: 38.22%; top: 68.42%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(0.992079);" role="presentation">single</span> <span dir="ltr" style="left: 43.04%; top: 68.42%; font-size: calc(var(--scale-factor)*10.91px); font-family: serif; transform: scaleX(0.993973);" role="presentation">short dsDNA molecule.</span></p>}, number={1}, journal={Journal of Self Assembly and Molecular Electronics}, author={Dachlika, Haya and Stern, Avigail and Rotem, Dvir and Porath, Danny}, year={2023}, month={Mar.}, pages={85–99} }